A 96 well format test using neat API or DMSO stock solutions with the automated Evolution liquid handling platform.
A complete, turnkey solution that will have you confidently measuring solubility vs. pH, in biorelevant media, in the presence of excipients, interpreting SAR, and evaluating aggregation effects. This information will promote faster, more productive and timely drug development timelines.
For increased magnitude response and better data integrity, there is also the option of using the The Gut-Box™. This is an important accessory that is designed with a built-in stirring mechanism, and is calibrated to specific speeds so that the PAMPA assay mimics the expected thickness of the aqueous boundary layer in the GIT.
Features:
- Spend less money with cost effective screening – less than $1per test
- Choose between scalable packages for various throughput needs and budgets
- Turnkey solution – Sole provider of complete solubility System
- Easy to use – Start testing quickly
- Predict solubility with sub-micromolar detection limit
- Comprehensive, integrated data processing & analysis software
- Easy integration with liquid handling platforms and detection systems
- Measurements in aqueous and simulated intestinal fluids
- Detection: from 50 ng/mL up to 2 mg/mL
- Full spectral shape analysis for impurity/decomposition detection
- HT excipient screening
- Get access to global support from world recognized solubility experts